Glyphosate is one of the most widely used herbicides globally, valued for its broad-spectrum effectiveness in controlling weeds. Classified as a non-selective herbicide, it targets both broadleaf weeds and grasses, making it a powerful solution for agriculture, forestry, and urban landscape management. Glyphosate works by inhibiting the EPSP synthase enzyme, which is crucial for plant growth, ultimately leading to plant death. It is highly soluble in water, available in liquid concentrates, granules, and other formulations, and often used in conjunction with genetically modified herbicide-resistant crops. Farmers rely on Glyphosate to maintain weed-free fields, promote higher yields, and support no-till farming practices that conserve soil health. Despite its benefits, Glyphosate has generated global debate due to potential health concerns, with some studies suggesting carcinogenic properties, though regulatory agencies remain divided. Additionally, overuse has led to herbicide-resistant weeds, posing long-term challenges for sustainable agriculture. While its acute toxicity to humans is relatively low, protective measures are necessary during spraying to avoid skin, eye, or respiratory exposure. Environmentally, Glyphosate can persist in soil and water, raising concerns about biodiversity and ecosystem impact. Despite controversies, it remains a cornerstone herbicide in modern farming, balancing efficiency with increasing demands for safer agricultural practices.